The game begins in 1933, in a place where it appears that the people believe in vampires, as all the doors and windows show crosses. It shows a man and woman running down a street. The woman trips, and the man pauses long enough to help her up, only to be dragged into a dark alleyway by a chain. His head is thrown from an alley at the woman's feet, with Rayne walking calmly up to the woman. The woman seemingly breaks down crying, but in fact only hides her face to reveal she is in fact a vampire. After a brief fight, Rayne decapitates her and then takes off before a small army of vampires tries to catch her off guard. She drops a grenade on their position as she leaves.

On top of the buildings, two mysterious men, who were watching the events unfold the whole time, are discussing their reason for being here. One reveals they are here to recruit Rayne, who is trying to find where her father is. The other member does not want a Dhampir with the Brimstone society, regardless of the fact that she is only half-vampire and has fewer weaknesses, as the Society is trying to rid the world of Vampires (and presumably people with Vampire blood in them). Eventually they agree to recruit Rayne, and leave a necklace with their symbol on it (as seen on the game cover).

MINIMUM

Windows 98/2000/ME/XP

Pentium III or AMD Athlon 800MHz Processor

256MB RAM

2GB Hard Disk Space

Nvidia TNT2, GeForce 1, 2 or 3, ATI Radeon 7000, 7200, 7500 or 8500, or Matrox G450 Video Card

DirectX Compatible Sound Card

DirectX 9

MAXIMUM

Windows 7/Vista (32 or 64 bit)

Intel i7 Quad Core 2.8Ghz or AMD equivalent

3GB System RAM (High)

30 GB Hard dDisk Space

nVidia GeForce 9800 GTX / ATI Radeon HD4850 Video Card

Direct X 9.0 compatible supporting Dolby Digital Live

DirectX 9.0 - DirectX 11